Uncontrolled Asthma Misdiagnosis: Is It Actually ABPA?
- MedBridge NZ
- 3 days ago
- 3 min read
Key Takeaways
Persistent Symptoms: If you are using 3+ asthma medications but still suffer from wheezing and chest tightness, you may be facing an uncontrolled asthma misdiagnosis.
Hidden Cause: A fungal condition called Allergic Bronchopulmonary Aspergillosis (ABPA) is often mistaken for severe asthma.
Targeted Testing: Standard asthma inhalers won't cure ABPA. Specific blood tests (IgE) and high-resolution CT scans are required for an accurate diagnosis.
Expert Access: MedBridgeNZ, a leading medical concierge provider, connects international patients with top respiratory specialists in China for advanced diagnosis and treatment.
Is Your "Severe Asthma" Actually an Uncontrolled Asthma Misdiagnosis?
For many patients, asthma is a manageable condition. However, a frustrating reality exists for a subset of sufferers: despite taking one, two, or even three types of asthma medications, symptoms persist. If you are constantly switching doctors and increasing dosages without relief, you might be a victim of uncontrolled asthma misdiagnosis.
According to Dr. Wu Shouquan, a specialist at the renowned West China Hospital of Sichuan University, the root cause of your suffering may not be typical allergic asthma at all. Instead, it could be a fungal infection known as Allergic Bronchopulmonary Aspergillosis (ABPA).

Understanding ABPA: A Common Culprit in Uncontrolled Asthma
Allergic Bronchopulmonary Aspergillosis (ABPA) is a hypersensitivity reaction to the fungus Aspergillus fumigatus. While less known than standard asthma, it is a frequent cause of uncontrolled asthma in young adults.
Dr. Wu highlights a concerning case that illustrates the dangers of misdiagnosis:
A 20-year-old woman had been on four different asthma medications for six months. Despite this aggressive treatment, her wheezing and chest tightness worsened, her lung function declined, and she began showing signs of bronchiectasis (permanent airway damage). Although early CT scans showed mild abnormalities, she continued to receive standard asthma treatment—a classic case of uncontrolled asthma misdiagnosis where the true fungal cause was ignored.
The Dangers of Ignoring Uncontrolled Asthma Symptoms
Distinguishing ABPA from standard asthma is critical. If left untreated due to a misdiagnosis, ABPA carries a higher risk of:
Rapid deterioration of lung function.
Respiratory failure.
Permanent bronchiectasis (irreversible widening of the airways).
Crucially, standard asthma inhalers (like Salbutamol, Budesonide, or Beclomethasone) alone cannot cure ABPA. Recognizing that your condition is an uncontrolled asthma misdiagnosis is the first step toward the right therapy.
Checklist: Signs Your Asthma Diagnosis Might Be Wrong
If you are under 30 and your uncontrolled asthma symptoms persist despite using 3 or more medications, Dr. Wu recommends a targeted set of investigations to rule out ABPA:
Serum Total IgE Test: Checks for elevated immune markers.
Aspergillus-Specific IgE Test: Checks for a specific reaction to the Aspergillus fungus.
High-Resolution Chest CT: To look for specific lung changes associated with fungal infection.
Clinical Insight: If your Total IgE is significantly elevated and your Aspergillus-Specific IgE is positive, there is a high suspicion that you are dealing with ABPA, not simple allergic asthma.
Correcting the Misdiagnosis: Effective Treatment Protocols
Once an uncontrolled asthma misdiagnosis is corrected to ABPA, the treatment strategy changes completely. Dr. Wu suggests:
Antifungal Medication: Such as Itraconazole.
Corticosteroids: Combined with antifungals in small doses to reduce inflammation.
Bronchoscopic Lavage: In severe cases where fungal infection is evident on a CT scan, a procedure to wash out the fungi and secretions may be necessary.
How MedBridgeNZ Facilitates Access to Expert Care
Correcting an uncontrolled asthma misdiagnosis requires expertise that general practitioners may lack. This is where Medical Tourism China becomes a viable option for patients seeking answers.
MedBridgeNZ is your trusted partner in navigating this journey. As a premium medical concierge provider, we do not provide medical services directly. Instead, we specialize in bridging the gap between international patients and top-tier Chinese hospitals, such as West China Hospital. We facilitate seamless access to experts like Dr. Wu, ensuring you receive the specialized opinion necessary to resolve your uncontrolled respiratory issues.
Conclusion
It is important to note that the majority of asthma cases are typical allergic asthma. However, if you fit the profile—under 30 years old, using multiple medications, with frequent attacks—do not ignore the possibility of a fungal cause. Investigating potential uncontrolled asthma misdiagnosis could save your lungs from permanent damage.
About the Source
Dr. Wu Shouquan (M.D., Ph.D., Postdoc)
Title: Attending Physician
Department: Department of Respiratory and Critical Care Medicine
Institution: West China Hospital, Sichuan University
Specialty: Expert in respiratory diseases and health education.
References
Original Video Title: 有的哮喘其实是可以根治的 (Some types of asthma can actually be cured)
Source URL: https://v.douyin.com/6qK8VxFjw7w/
Content Creator: Dr. Wu Shouquan (Douyin ID: healthhelp)
Disclaimer: This article is for educational purposes only and does not constitute medical advice. Please consult with a healthcare professional for diagnosis and treatment.



