Professional Title & Qualifications:
Chief Physician, Doctoral Supervisor
Specialization:
Hospital & Department：
Shanghai Renji Hospital, Jiao Tong University – Department of Gastrointestinal Surgery
Dr. Zizhen Zhang - Gastrointestinal Surgery Specialist
Personal Biography
Currently serves as the Director of the Department of Gastrointestinal Surgery at Renji Hospital, affiliated with Shanghai Jiao Tong University School of Medicine. He is a Chief Physician, PhD in Surgery, and Doctoral Supervisor. He began his career in 2004 and has long been engaged in the field of general surgery, specializing in gastrointestinal tumor surgery and minimally invasive surgery. From May 2014 to April 2015, he was a visiting scholar at the Mannheim Medical College of Heidelberg University in Germany, studying under the renowned European surgical oncologist Professor Peter Hohenberg.
He has served as a Master's Supervisor at Shanghai Jiao Tong University School of Medicine since 2019. In October 2020, he was appointed Deputy Director of Gastrointestinal Surgery, overseeing administrative work at the West Campus of Renji Hospital. He became the interim Director in January 2024 and was appointed Director of the Department of Gastrointestinal Surgery in September 2024.
Book an online consultation with Dr. Zizhen Zhang
Areas of Expertise
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Minimally invasive surgery (laparoscopic and robotic) and comprehensive treatment for gastrointestinal tumors.
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Specializes in standardized, individualized, and precision treatment for gastric cancer, colorectal cancer, and gastrointestinal stromal tumors.
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Da Vinci robotic surgery for gastrointestinal malignancies.
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Minimally invasive surgery for common general surgery conditions such as inguinal hernia, appendicitis, cholecystitis, and thyroid tumors.
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Extensive experience in function-preserving minimally invasive surgery for early gastric cancer, such as Pylorus-Preserving Gastrectomy (PPG).
Clinical Highlights
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Over 4,200 patients treated
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100% treatment satisfaction rate
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100% patient satisfaction with service attitude
Work Experience
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Sept 2024 - Present: Director, Department of Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine
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Jan 2024 - Sept 2024: Interim Director, Department of Gastrointestinal Surgery, Renji Hospital
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Oct 2020 - Sept 2024: Deputy Director of Administration, Department of Gastrointestinal Surgery, Renji Hospital
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Dec 2017 - Present: Associate Chief Physician, Department of Gastrointestinal Surgery, Renji Hospital
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May 2014 - May 2015: Visiting Scholar, Department of Surgical Oncology, Mannheim Medical College, Heidelberg University, Germany
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Dec 2012 - Dec 2017: Attending Physician, Department of Gastrointestinal Surgery, Renji Hospital
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Aug 2004 - Dec 2012: Resident Physician, Department of Gastrointestinal Surgery, Renji Hospital
Education Experience
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PhD, Surgery: Shanghai Jiao Tong University School of Medicine
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Master's, Surgery: Shanghai Jiao Tong University School of Medicine
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Bachelor's, Clinical Medicine: Shanghai Jiao Tong University School of Medicine
Social Positions
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Committee Member, Chinese Anti-Cancer Association (CACA), Gastrointestinal Stromal Tumor (GIST) Professional Committee
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Deputy Head, Gastrointestinal Surgery Working Group, General Surgery Branch, Shanghai Medical Doctor Association
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Committee Member, Minimally Invasive Surgery Group, General Surgery Branch, Shanghai Medical Association
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Adjunct Professor (CBL), China-Canada Joint Institute
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Master's Supervisor (Surgery), Shanghai Jiao Tong University School of Medicine
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Group Leader, Gastrointestinal Tumor MDT Diagnosis and Treatment Center, Renji Hospital (West Campus)
Awards and Honors
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Shanghai Talent Development Fund
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First and Second "Climbing Program" for Young Scholars in General Surgery, China
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Shanghai Municipal Health Commission Young Physician Training Grant
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"Kowloon" Medical Excellent Young Talent Award, Shanghai Jiao Tong University School of Medicine
Research Achievements
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Principal Investigator: Leads several national-level projects, including:
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National Natural Science Foundation (No. 82173215): "Mechanism exploration of tumor-associated macrophages promoting gastric cancer liver metastasis..."
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National Natural Science Foundation (No. 81972206): "Research on the mechanism of LOX-TGF-β1 axis-mediated co-evolution of tumors and cancer-associated fibroblasts..."
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National Natural Science Foundation, Youth Project (No. 81302094): "Long-chain non-coding RNA-LINC00628..."
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Selected Publications (as first or corresponding author):
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Danhua Xu, Enhao Zhao, Chunchao Zhu, et al., Zizhen Zhang*. TIGIT and PD-1 may serve as potential prognostic biomarkers for gastric cancer. Immunobiology, 2020.
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Zizhen Zhang, Chaojie Wang, Yeqian Zhang, et al. CircDUSP16 promotes the tumorigenesis and invasion of gastric cancer by sponging miR-145-5p. Gastric Cancer. 2020.
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Wang CJ, Zhu CC, Xu J, et al., Zhang ZZ*. The lncRNA UCA1 promotes proliferation, migration, immune escape and inhibits apoptosis in gastric cancer... Mol Cancer. 2019.
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Zi-Zhen Zhang#, Gang Zhao#, Chun Zhuang#, et al. Long non-coding RNA LINC00628 functions as a gastric cancer suppressor... Scientific Reports, 2016.
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Zi-Zhen Zhang#, Zhi-Yong Shen#, Yan-Ying Shen, et al. HOTAIR long noncoding RNA promotes gastric cancer metastasis... Molecular Cancer Therapeutics, 2015.
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*The doctor’s information is sourced from the hospital’s official website or provided directly by the doctor. Due to update cycles, there may be occasional delays in reflecting the most recent changes.